Artists often talk about "negative space" when analyzing or creating paintings. It struck me that negative space is a useful metaphor for anything. In basketball, negative space may mean cutting away from the ball and setting picks across the court. In business, it may mean thinking about the little things on the edges of an idea which, when tweaked, turn the idea from foolish to brilliant. (See my post about thinking 1 degree differently.) About.com Painting says:
Negative space is very useful when confronted with ‘difficult’ subjects, such as hands. Instead of thinking about fingers, nails, knuckles, start by looking at the shapes between the fingers. Then look at the shapes around the hand, for example the shape between the palm and the wrist. Laying these in will give you a good basic form on which to build.
And to wrap it up with a visual: